2014
Date: 2017-11-10
- A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 Yue W, Chen ZH, Liu HY, Yan C, Chen M, Feng D, Yan CJ, Wu H, Du L, Wang YY, Liu JH, Huang XH, Xia LX, Liu L, Wang XH, Jin HJ, Wang J, Song ZY, Hao XJ*, Chen Q*. Cell Research, 2014; 24(4):482-496
- A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy Chen G, Han Z, Feng D, Chen YF, Chen LB, Wu H, Huang L, Zhou CQ, Cai XY, Fu CY, Duan LW, Wang XH, Liu L, Liu XQ, Shen YQ, Zhu YS*, Chen Q*. Molecular Cell, 2014; 54(3):362-377
- Receptor-mediated mitophagy in yeast and mammalian systems Liu L, Sakakibara K, Chen Q*, Okamoto K*. Cell Research, 2014; 24(7):787-795\
- Ping XL, Sun BF, Wang L, Xiao W, Yang X, Wang WJ, Adhikari S, Shi Y, Lv Y, Chen YS, Zhao X, Li A, Yang Y, Dahal U, Lou XM, Liu X, Huang J, Yuan WP, Zhu XF, Cheng T, Zhao YL, Wang XQ, Danielsen JMR, Liu F*, Yang YG*.Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase. Cell Research, 2014; 24(2):177-189
- Gao M, Wei W, Li MM, Wu YS, Ba ZQ, Jin KX, Liao YQ, Adhikari S, Chong ZC, Zhang T, Guo CX, Tang TS, Zhu BT, Xu XZ, Mailand N, Yang YG*, Qi YJ*, Danielsen JMR. Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination. Cell Research, 2014; 24(5):532-541
- Zhang JY, Zheng KW, Xiao S, Hao YH, Tan Z*. Mechanism and Manipulation of DNA: RNA Hybrid G-Quadruplex Formation in Transcription of G-Rich DNA. Journal of the American Chemical Society, 2014; 136(4):1381-1390
- Wu H, Xue D, Chen G, Han Z, Huang L, Zhu C, Wang X, Jin H, Wang J, Zhu Y, Liu L*, Chen Q*. The BCL2L1 and PGAM5 axis defines hypoxia-induced receptor-mediated mitophagy. Autophagy, 2014; 10(10):1712-1725\
- Xiao S, Zhang JY, Wu J, Wu RY, Xia Y, Zheng KW, Hao YH, Zhou X, Tan Z*. Formation of DNA: RNA Hybrid G-Quadruplexes of Two G-Quartet Layers in Transcription: Expansion of the Prevalence and Diversity of G-Quadruplexes in Genomes. Angew Chem Int Ed Engl., 2014; 53(48):13110-13114
- Wang K, Liu F, Zhou LY, Long B, Yuan SM, Wang Y, Liu CY, Sun T, Zhang XJ, Li PF*. The Long Noncoding RNA CHRF Regulates Cardiac Hypertrophy by Targeting miR-489. Circulation Research, 2014; 114(9):1377-1388
- Wang K, Long B, Zhou LY, Liu F, Zhou QY, Liu CY, Fan YY, Li PF*. CARL lncRNA inhibits anoxia-induced mitochondrial fission and apoptosis in cardiomyocytes by impairing miR-539-dependent PHB2 downregulation. Nature Communications, 2014;5:3596
- Zhang CX, Lv JH, He QP, Wang SF, Gao Y, Meng AM, Yang X, Liu F*. Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence. Nature Communications, 2014;5:3431
- Ji SM, Sun M, Zheng XD, Li L, Sun LW, Chen DH*, Sun QM*.Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signalling by controlling MyD88 turnover in Drosophila. Nature Communications, 2014;5:3458
- Zhu LN, Yang T, Li LJ, Sun LN, Hou YZ, Hu XL, Zhang LJ, Tian HL, Zhao QJ, Peng JX, Zhang HB, Wang RY, Yang ZZ, Zhang LF, Zhao Y*. TSC1 controls macrophage polarization to prevent inflammatory disease. Nature Communications, 2014;5: 4696
- Liu Y, Yang YR, Tang TS, Zhang H, Wang ZF, Friedberg E, Yang W*, Guo CX*. Variants of mouse DNA polymerase κ reveal a mechanism of efficient and accurate translesionsynthesis past a benzo[a]pyrene dG adduct. Proceedings of the National Academy of Sciences of the United States of America, 2014; 111(5):1789-1794
- Wei YL, Ma DY, Gao Y, Zhang CX, Wang L, Liu F*. Ncor2 is required for hematopoietic stem cell emergence by inhibiting Fos signaling in zebrafish. Blood, 2014;124(10):1578-1585
- Zheng KW, Wu RY, He YD, Xiao S, Zhang JY, Liu JQ, Hao YH, Tan Z*. A competitive formation of DNA: RNA hybrid G-quadruplex is responsible to the mitochondrial transcription termination at the DNA replication priming site. Nucleic Acids Research, 2014; 42(16):10832-10844
- Shrestha P, Xiao S, Dhakal S, Tan Z*, Mao HB*. Nascent RNA transcripts facilitate the formation of G-quadruplexes. Nucleic Acids Research, 2014; 42(11):7236-7246
- Bo L, Su-Ling D, Fang L, Lu-Yu Z, Tao A, Stefan D, Kun W*, Pei-Feng L*Autophagic program is regulated by miR-325. Cell Death and Differentiation, 2014; 21(6):967-977
- Huang Q, Tang X, Wang G, Fan Y, Ray L, Bergmann A, Belenkaya TY, Ling X, Yan D, Lin Y, Ye X, Shi W, Zhou X, Lu F, Qu J*, Lin X*. Ubr3 E3 ligase regulates apoptosis by controlling the activity of DIAP1 in Drosophila. Cell Death & Differentiation, 2014;21(12):1961-1970
- Wang K, Sun T, Li N, Wang Y, Wang JX, Zhou LY, Long B, Liu CY, Liu F, Li PF*. MDRL lncRNA Regulates the Processing of miR-484 Primary Transcript by Targeting miR-361. Plos Genetics, 2014; 10(7):12
- Sun B, Hu XL, Liu GW, Ma B, Xu YM, Yang T, Shi JF, Yang F, Li HR, Zhang LF*, Zhao Y*. Phosphatase Wip1 Negatively Regulates Neutrophil Migration and Inflammation. Journal of Immunology, 2014; 192(3):1184-1195
- Hou YZ, Lin HJ, Zhu LN, Liu ZT, Hu FL, Shi JF, Yang T, Shi XY, Guo HF, Tan XT, Zhang LF, Wang Q*, Li ZG*, Zhao Y*.The Inhibitory Effect of IFN-gamma on Protease HTRA1 Expression in Rheumatoid Arthritis. Journal of Immunology, 2014; 193(1):130-138
- Liu Z, Ma L, Wen ZS, Hu Z, Wu FQ, Li W, Liu JS, Zhou GB*.Cancerous inhibitor of PP2A is targeted by natural compound celastrol for degradation in non-small-cell lung cancer. Carcinogenesis, 2014; 35 (4):905-914
- Wang FL, Fischhaber PL, Guo CX, Tang TS*. Epigenetic modifications as novel therapeutic targets for Huntington's disease. Epigenomics, 2014;6(3):287-297
- Liu F, Li N, Long B, Fan YY, Liu CY, Zhou QY, Murtaza I, Wang K*, Li PF*. Cardiac hypertrophy is negatively regulated by miR-541. Cell Death & Disease, 2014; 5:10
- Li Q, Wang JX, He YQ, Feng C, Zhang XJ, Sheng JQ, Li PF*. MicroRNA-185 regulates chemotherapeutic sensitivity in gastric cancer by targeting apoptosis repressor with caspase recruitment domain. Cell Death & Disease, 2014; 5:12
- Li M, Xia PY, Du Y, Liu SW, Huang GL, Chen J, Zhang HL, Hou N, Cheng X, Zhou LY, Li PF, Yang X*, Fan ZS*.T-cell Immunoglobulin and ITIM Domain (TIGIT) Receptor/Poliovirus Receptor (PVR) Ligand Engagement Suppresses Interferon-gamma Production of Natural Killer Cells via beta-Arrestin 2-mediated Negative Signaling. Journal of Biological Chemistry, 2014; 289(25):17647-17657
- Li XL, Qu FQ, Xie WJ, Wang FL, Liu HM, Song SH, Chen TT, Zhang Y, Zhu S, Wang Y, Guo CX, Tang TS*. Transcriptomic Analyses of Neurotoxic Effects in Mouse Brain After Intermittent Neonatal Administration of Thimerosal. Toxicological Sciences, 2014;139(2):452-465
- Guo YQ, Li ZH*, Lin XH*. Hs3st-A and Hs3st-B regulate intestinal homeostasis in Drosophila adult midgut. Cellular Signalling, 2014;26(11):2317-2325
- Feng Y, Li X, Ray L, Song HY, Qu J, Lin SY*, Lin XH*.The Drosophila tankyrase regulates Wg signaling depending on the concentration of Daxin. Cellular Signalling, 2014; 26(8):1717-1724
- Gorsi B*, Liu F, Ma X, Chico TJA, Shrinivasan A, Kramer KL, Bridges E, Monteiro R, Harris AL, Patient R, Stringer SE. The heparan sulfate editing enzyme Sulf1 plays a novel role in zebrafish VegfA mediated arterial venous identity. Angiogenesis, 2014; 17(1):77-91
- Zhou B, Yun EY, Ray L, You J, Ip YT, Lin XH*. Retromer Promotes Immune Quiescence by Suppressing Spatzle-Toll Pathway in Drosophila. Journal of Cellular Physiology, 2014; 229(4):512-520
- Deng XB, Zhang F, Wang LJ, Rui W, Long F, Zhao Y*, Chen DL, Ding WJ*. Airborne fine particulate matter induces multiple cell death pathways in human lung epithelial cells. Apoptosis, 2014; 19(7):1099-1112
- Liu YH, Xiao QC, Liu YQ, Li Z, Qiu YT, Zhou GB*, Yao ZJ*, Jiang S*. Biological evaluation of new mimetics of annonaceous acetogenins: Alteration of right scaffold by click linkage with aromatic functionalities. European Journal of Medicinal Chemistry, 2014; 78:248-258
- Wu TT, Zhao Y*. The roles of myeloid-derived suppressor cells in transplantation. Expert Review of Clinical Immunology, 2014; 10(10):1385-1394
- Shen X, Du J, Zhao Y*, Guan W. Phosphatase Wip1 as a new therapeutic target for intestinal ischemia-reperfusion injury. Expert Rev Clin Immunol. 2014; 10(12):1591-1595
- Shen XF, Du JF, Guan WX*, Zhao Y*.The balance of intestinal Foxp3(+) regulatory T cells and Th17 cells and its biological significance. Expert Review of Clinical Immunology, 2014; 10(3):353-362
- Liu Z, Ma L, Wen ZS, Cheng YX, Zhou GB*. Ethoxysanguinarine Induces Inhibitory Effects and Downregulates CIP2A in Lung Cancer Cells. Acs Medicinal Chemistry Letters, 2014; 5(2):113-118
- Zhang QH, Zhang Y, Wu LF, Yang YF, Li X, Gao L, Hou XM, Wu YH, Hou GL, Li ZH*, Lin XH*. dBrms1 Acts as a Positive Regulator of Notch Signaling in Drosophila Wing. Journal of Genetics and Genomics, 2014; 41(6):317-325
- Guo YQ, Feng Y, Li ZH*, Lin XH*. Drosophila heparan sulfate 3-O sulfotransferase B Null Mutant Is Viable and Exhibits No Defects in Notch Signaling. Journal of Genetics and Genomics, 2014; 41(7):369-378
- Huang XD, Shi L, Cao J, He FF, Li RL, Zhang Y, Miao S, Jin LJ, Qu J, Li ZH*, Lin XH*. The Sterile 20-Like Kinase Tao Controls Tissue Homeostasis by Regulating the Hippo Pathway in Drosophila Adult Midgut. Journal of Genetics and Genomics, 2014; 41(8):429-438
- Sun LN, Li HR, Luo HY, Zhao Y*. Thymic Epithelial Cell Development and Its Dysfunction in Human Diseases. Biomed Research International, 2014; 206929
- Wang X, Luan Q*, Chen Q, Zhao L, Guo Y. Mitochondrial polymorphisms and dysfunction related to aggressive periodontitis: a pilot study. Oral Diseases, 2014; 20(5):490-498
- Yan C, Huang L, Liu HC, Chen DZ, Liu HY, Li XH, Zhang Y, Geng MY, Chen Q*, Hao XJ*. Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells. Bioorganic & Medicinal Chemistry Letters, 2014; 24(8):1884-1888
- Liu YH, Liu YQ, Li Z, Zhou GB, Yao ZJ*, Jiang S*. Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy. Bioorganic & Medicinal Chemistry Letters, 2014;24(7):1650-1653
- Wang GL, Tang XF, Chen YJ, Cao J, Huang QZ, Ling XM, Ren WY, Liu SQ, Wu YH, Ray L, Lin XH*. Hyperplastic discs differentially regulates the transcriptional outputs of hedgehog signaling. Mechanisms of Development, 2014; 133:117-125
- Wang Y, Sun T, Wang K, Wang JX, Li PF*. PiRNAs link epigenetic modifications to reprogramming. Histol Histopathol, 2014; 29(12):1489-1497
- Zhu Y, Chen G, Chen L, Zhang W, Feng D, Liu L, Chen Q*. Monitoring mitophagy in Mammalian Cells. Methods in Enzymology, 2014; 547:39-55
- Wang CZ, Luo HY, Zhu LN, Yang F, Chu ZL, Tian HL, Feng MF, Zhao Y*, Shang P*. Microgravity inhibition of lipopolysaccharide-induced tumor necrosis factor-a expression in macrophage cells. Inflamm Res, 2014;63(1):91-98
- Qu A, Wang H, Li JN, Wang JJ*, Liu JJ, Hou YZ, Huang L, Zhao Y. Biological Effects of I-125 Seeds Radiation on A549 Lung Cancer Cells: G2/M Arrest and Enhanced Cell Death. Cancer Investigation, 2014;32(6):209-217
- Luo HY, Wang CZ, Feng MF, Zhao Y*. Microgravity Inhibits Resting T Cell Immunity in an Exposure Time-Dependent Manner. International Journal of Medical Sciences, 2014; 11(1):87-96
- Fan YY, Long B, Liu F, Zhou LY, Wang K, Li PF*. Establishment of Cardiomyocyte-specific miR-30b Transgenic Mice and Exploring The Function of miR-30b. Progress in Biochemistry and Biophysics, 2014; 41(6):575-582
- Li ZH*, Guo YQ, Han LL, Zhang Y, Shi L, Huang XD, Lin XH*. Debra-Mediated Ci Degradation Controls Tissue Homeostasis in Drosophila Adult Midgut. Stem Cell Reports, 2014; 2(2):135-144
- You J, Zhang Y, Li ZH, Lou ZF, Jin LJ, Lin XH*. Drosophila Perlecan Regulates Intestinal Stem Cell Activity via Cell-Matrix Attachment. Stem Cell Reports, 2014; 2(6):761-769
- Zhu GZ, Li YJ, Zhu F, Wang T, Jin WS, Mu W, Lin W, Tan WQ, Li WQ, Street RC, Peng SY, Zhang J, Feng Y, Warren ST, Sun QM*, Jin P*, Chen DH*. Coordination of Engineered Factors with TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming. Stem Cell Reports, 2014;2(3):253-261